Saliva with biomarkers – non invasive technique for detecting diseases
Posted by evolvingwheel on December 7, 2007
I have been stumbling upon this concept on and off and finally decided to post it. I have come across two articles. One is a post on Popular Science website and the other a research paper from nearly 3 years back. The Pop Sc. article talks about the potential of detecting diseases from human saliva.
Earlier, saliva was ignored due to a very low number of analytes present in it. But with the new human saliva proteomic project and new biomarkers being discovered, spit is realistically being considered as a non-invasive point-of-care diagnostic platform. I am all for it. Just think how easy it would be – just spit and detect the marker. No need to even show up at the clinic. Mail the specimen if time allows. Stress capability of saliva to withstand temperature and pressure is better than blood. Read the Pop Sci article [here].
Now the paper from 2005. It is a research article co-athored by scientists from several institutions in CA. The paper talks about MEMS diagnostic chip using saliva. Gives an overview of mico-electro mechanical system / nano-electro mechanical system (MEMS/NEMS) sensors to oral fluids for diagnostic purposes. Please read the article [here]. As a proponent of cheap diagnostics that can be used for social innovation in underserved communities, I am highly interested in learning more about the potential of MEMS chips. I will cover more soon.
Another good link: http://www.tastechip.com/saliva/saliva_diagnostics_research.html